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Since May 10th 2008


Initial G




Ginkgo biloba
Glycyrrhiza glabra
Gentiana lutea
Gentiana scabra
Guazuma ulmifolia


 

 

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Guazuma ulmifolia Lamk (Sterculiace)

Synonyms
Guazuma tomentosa Kunth.

Local names
Bastard Cedar, mutamba, jati belanda

Description
Guazuma ulmifolia grows to 30 m in height and 30-40 cm in diameter with a rounded crown. Young twigs covered with rust-brown or light grey star-shaped hairs. Bark grey or grey-brown becoming furrowed and rough or slightly shaggy. Leaves alternate in 2 rows in flattened arrangement, ovate to lance-shaped, 6-13 cm long, 2.5-6 cm wide, long-pointed, finely saw-toothed, with 3 or sometimes 5 main veins from rounded or notched unequal-sided base, thin, nearly hairless or sometimes densely hairy, green upper surface, paler underneath; at night hanging vertically. Leaf stalks slender, 6-12 mm long, covered with tiny star-shaped hairs. Flower clusters (panicles) branched, 2.5-5 cm long, at the base of leaves. Flowers many, short stalked, small, brownish-yellow, with 5 parts, about 1 cm long and half as broad, spreading, slightly fragrant. Calyx with 2-3 lobes, with rusty brown or light grey hairs, turned back, and then greenish; 5 yellow petals, each 2-forked; a yellowish stamen column with about 15 anthers surrounding the pistil, which has a hairy, light-green 5-celled ovary, style and 5 united stigmas. Fruit round to elliptical capsules, very warty, hard, black, 15-25 mm long, 5-celled, opening at tip or irregularly by pores. Seeds many, egg-shaped, 3 mm long, grey. The specific epithet alludes to its elm-like leaves.

Plant material used
Leaves

Major chemical constituents
The plant gave kaempferol glycosides. Leaves contain octacosanol and taraxerol-OAC, friedelin-3-alpha- OAC, 3 beta-ol and beta-sitosterol, caryophyllene, catechins, farnesol, friedelin, kaurenoic acid, precocene I, procyanidin B-2, procyanidin B-5, procyanidin C-1. Bark contains friedelin, betulin and beta-sitosterol.

Dosage forms
Dried leaves powder

Medicinal uses
Uses supported by clinical data
Weight loss (pre-clinical)

Uses described in pharmacopoeias and well established documents
Analeptic, Antibacterial, Antidote, Comocladia, Antiherpetic, Antiprostaglandin, Antiseptic, Antiviral, Aperitif, Astringent, Bronchodilator, CNS-Stimulant, Cytotoxic, Depurative, Diaphoretic, Diuretic, Emollient, Hemostat, Pectoral, Respirtory stimulant, Stomachic, Uterotonic

Uses described in traditional medicine
Alopecia, Anorexia, Asthma, Bacteria, Bleeding, Bronchosis, Cancer, Childbirth, Cold, Cough, Dermatosis, Diarrhea, Dislocation, Dysentery, Elephantiasis, Fever, Flu, Gonorrhea, Heatstroke, Hemorrhoid, Hepatosis, Herpes, Infection, Leprosy, Malaria, Nephrosis, Parasite, Pneumonia, Proctosis, Prostatosis, Pulmonosis, Rash, Shigella, Sore, Sore Throat, Staphylococcus, Syphilis, Virus, Water Retention

Proven pharmacological activity
Animal studies
Antimicrobial, anticancer, hair-loss, anti-inflammation, antiulcer, ACE inhibitor, antioxidant, antidiabet, anticholesterol, hypotensive

Human studies
Weight loss (pre-clinical)
Hair loss

Toxicity
Categorized as nontoxic
LD50 =>25,000 mg/kg oral rat
LD50 = 5975 mg/kg intraperitoneal rat.

Contraindications
Pregnancy

Warnings
No data available

Precautions
Drug interactions
Possible potentiating effect with ACE inhibitor (e.g: captopril) and other antihypertensive medication.

Laboratory test interactions
No data available

Carcinogenesis, mutagenesis
Non carcinogenic

Pregnancy
Has uterus stimulant activity, avoid in pregnancy

Nursing mothers
No data available, therefor avoid it

Paediatric use
No data available, therefor avoid it

Adverse reactions
No data available

Posology
For body slimming purpose, take 20 g of dried leave, add 200 ml of hot water, let cool then filter with clean cloth. Divide into 2 equal subdoses for one day

 

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