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Cephaelis ipecacuanha
Commiphora molmol
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Crocus sativus
Cordyceps sinensis
Cyperus rotundus


 

 

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Cordyceps sinensis (Clavicipitaceae)

Synonyms

Local Names
Chinese Caterpiller fungus, Summer Plant Winter Worm, Dong Chong Xia Cao, Yarsha Gumba, Semitake, Yung Chung Tsao, JinShuBao

Description
Cordyceps is a unique black, blade- shaped fungus found primarily at high altitude on the Qinghai-Tibetan plateau. The fungus is parasitic, growing on and deriving nutrients from several species of caterpillar, although primarily that of the moth Hepialus armoricanus Oberthur, which lives 6 inches underground. In late autumn, chemicals on the skin of the caterpillars interact with the fungal spores and release the fungal mycelia, which then infect the caterpillar. By early summer of the following year, the fungal infestation has killed the caterpillar and the fruiting body can be seen protruding from the caterpillar's head. This wild form, Cordyceps sinensis, is harvested, whereas the principal fungal mycelium of Cordyceps sinensis, known as Paecilomyces hepiali Chen, is cultivated aseptically.

Plant material used
Micelium

Major chemical constituents
Cordycepic acid, glutamic acid, amino acids (phenylalanine, proline, histidine, valine, oxyvaline, arginine); Polyamines (1,3-diamino propane,, cadaverine, spermidine, spermine, homospermidine, and purtescine); Cyclic dipeptides (cyclo-(gly-pro), cyclo-(leu-pro), cyclo-(valpro), cyclo-(ala-leu), cyclo-(ala-val) and cyclo-(thr-leu); Saccharides and sugar derivatives (d-mannitol, oligosaccharides, and polysaccharides); Sterols (ergosterol, delta-3 ergosterol, ergosterol peroxide, 3-sistosterol, daucosterol and campasterol); Nucleotides and nucleosides (adenine, uracil, uridine, guanine, guanosine, thymidine, and deoxyuridine and cordycepin); 28 saturated and unsaturated fatty acids, their derivatives and other organic acids (oleic, linoleic, palmitic and stearic acids); Vitamins (B1, B2, B12, E and K); Inorganic elements (K, Na, Ca, Mg, Fe, Cu, Mn, Zn, Pi, Se, Al, Si, Ni, Sr, Ti, Cr, Ga, V, and Zr).

Medicinal uses
Uses supported by clinical data
Immunostimulant and immunomodulator.
Ameliorate symptoms of aging including significant alleviation of fatigue, cold intolerance, dizziness, frequent nocturia, tinnitus, hyposexuality, and amnesia.
Anticholestrol and hyperlipidemia.
Enhance sexual performance
Anticancer
Tinnitus, chronic nephritis, arrhythmia
Renoprotective

Uses described in pharmacopoeias and well established documents
Immunostimulation & Immunomodulation, Anti-tumor, Bronchitis, Asthma, Tuberculosis, Hepatitis, Impotence, Liver disease, Anti-fatigue, Anti-inflammatory, Atherosclerosis, Hyperlipidemia

Uses described in traditional medicine
Immunostimulation & Immunomodulation, Anti-tumor, Bronchitis, Asthma, Tuberculosis, Hepatitis, Impotence, Liver disease, Anti-fatigue, Anti-inflammatory, Atherosclerosis, Hyperlipidemia

Proven pharmacological activity
Animal studies
Immunostimulant and Immunomodulator.
Increase oxygen use efficiency.
Anti-cancer and anti-tumor activities.
Strong antioxidant.
Enhance sexual performance
Liver protective
Anticholestrol

Human studies
Immunostimulant and immunomodulator.
Ameliorate symptoms of aging including significant alleviation of fatigue, cold intolerance, dizziness, frequent nocturia, tinnitus, hyposexuality, and amnesia.
Anticholestrol and hyperlipidemia.
Enhance sexual performance
Anticancer
Tinnitus, chronic nephritis, arrhythmia
Renoprotective

Contraindications
No data available

Warnings
No information available.

Precautions
Drug interactions
Possible potentiating effect with coumadin (warfarin) or any anticoagulant medication.
Possible potentiation with MAOB inhibitor.

Carcinogenesis, mutagenesis
Non carcinogenic

Use in Pregnancy
Has not been evaluated in children and should only be used by adults. Because there are not adequate and well controlled studies in pregnant or lactating women, this product should not be used during pregnancy or lactation without the advice of a physician.

Paediatric use
Has not been evaluated in children and should only be used by adults. Because there are not adequate and well controlled studies in pregnant or lactating women, this product should not be used during pregnancy or lactation without the advice of a physician.

Adverse reactions
Considered to be very safe, if any, clinical trials revealed very few minor side effects to supplementation, such as thirst or heartburn, which decreased with continued use or if the supplement was taken before meals.

Dosage forms
Dried micellium

Posology
1000 mg/day

 

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